Table 3.
Detailed information about the 13 differentially expressed proteins reported more than three times in the H&L PCa group
| Gene IDa | Gene symbol | Protein name | Frequency of occurrence | Differentially expressedb |
|---|---|---|---|---|
| 55 | ACPP | Acid phosphatase, prostate | 4 | 1 up, 2 downc |
| 3309 | HSPA5 | Heat shock 70 kDa protein 5 | 4 | 3 up, 1 down |
| 7414 | VCL | Vinculin | 4 | 2 up, 2 down |
| 87 | ACTN1 | Actinin, alpha 1 | 3 | Downregulation |
| 301 | ANXA1 | Annexin A1 | 3 | 1 up, 1 down |
| 563 | AZGP1 | Alpha-2-glycoprotein 1, zinc binding | 3 | Upregulation |
| 1292 | COL6A2 | Collagen, type VI, alpha 2 | 3 | 1 up, 1 down |
| 1674 | DES | Desmin | 3 | Downregulation |
| 2316 | FLNA | Filamin A, alpha | 3 | Downregulation |
| 4000 | LMNA | Lamin A/C | 3 | 2 up, 1 down |
| 4191 | MDH2 | Malate dehydrogenase 2, NAD (mitochondrial) | 3 | 2 up, 1 down |
| 4627 | MYH9 | Myosin, heavy chain 9, non-muscle | 3 | 1 up, 1 down |
| 7094 | TLN1 | Talin 1 | 3 | 1 up, 1 down |
Notes:
a
The listed gene IDs are for the human species.
b
Information on the protein expression is based on results from the proteomics literature.
c
This protein was reported once as upregulated and reported twice as downregulated. In this table, the frequency with which proteins are reported is not consistent with the frequency of expression because some studies did not provide expression information.
Abbreviations: PCa, prostate cancer; H&L, high and low PCa metastatic tendencies; ID, identification.