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. 2016 Mar 16;9:1559–1569. doi: 10.2147/OTT.S100050

Table 2.

Kaplan–Meier survival analysis (log-rank test) according to USP7 expression in patients with EOC

Variables Cases
(n=141)
Overall survival time (months)
P-value#
Mean Median
Age (years) 0.004*
≤60 103 83.07 82
>60 38 57.09 60
FIGO stage 0.020*
I–II 46 91.68 88
III–IV 95 68.96 68
Histology type 0.483
Serous 121 74.90 72
Non-serous 20 84.09 82
Pathological grade 0.037*
G1–G2 97 81.80 81
G3 44 64.89 60
Lymph node metastasis 0.005*
No 64 89.45 83
Yes 77 64.48 66
Preoperative CA-125 (U/mL) 0.795
≤900 73 78.20 82
>900 68 74.89 72
USP7 expression 0.003*
Low expression 82 85.75 83
High expression 59 62.34 60

Notes:

#

Log-rank correlation test.

*

Statistically significant.

Abbreviations: USP7, ubiquitin-specific protease 7; EOC, epithelial ovarian cancer; FIGO, International Federation of Gynecology and Obstetrics; CA, cancer antigen.