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A schematic representation of the hypothesis on pathways of filtered capillary fluid and peritoneal fibrosis. Note that measurements of free water transport in drained effluent are not necessarily representative of capillary and venular aquaporin-1 function, because of the peritoneal interstitial barrier. FWT = free water transport; SPFT = small pore fluid transport; AQP-1 = aquaporin-1.
