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. Author manuscript; available in PMC: 2016 Mar 22.
Published in final edited form as: Mod Pathol. 2014 Apr 18;27(11):1499–1509. doi: 10.1038/modpathol.2014.50

Figure 1.

Figure 1

Adenoma-like (right) and hepatocellular carcinoma (left) portions in a 52-year-old man (a, H&E, × 10). The adenoma-like portion showed inflammatory features and was positive for SAA (b, × 10). Both adenoma-like (c, × 10) and hepatocellular carcinoma portions (d, × 20) showed β-catenin activation as evidenced by diffuse glutamine synthetase staining; nuclear β-catenin was observed only in the HCC portion (e, × 20). FISH showed chromosome 1 gains in both adenoma-like (f, × 100) and hepatocellular carcinoma portions (g, × 100).