TABLE 2.

Univariate and Multivariate Analyses of Predictors of Rapid Tumor Progression^*

Predictor Variables	OR (95% CI)	P Value
Univariate analysis
Age at T1 diagnosis (per year)	1.02 (0.96-1.08)	0.56
Sex, female	0.76 (0.26-2.28)	0.63
Race/ethnicity (versus Caucasian)
Hispanic	4.47 (1.29-15.46)	0.02
African American	3.83 (0.55-26.68)	0.17
Asian	1.19 (0.37-3.78)	0.77
Diagnosis of liver disease (versus HCV)
Alcohol	6.67 (1.49-29.91)	0.01
NASH	0.30 (0.04-2.54)	0.27
HBV	0.13 (0.02-1.07)	0.06
CTP score (per point)	1.06 (0.81-1.38)	0.66
MELD score (per point)	1.04 (0.92-1.17)	0.57
Tumor size at T1 diagnosis (per cm)	1.98 (0.40-9.90)	0.41
AFP at T1 diagnosis
≥20 (versus<20)	1.87 (0.71-4.92)	0.20
≥100 (versus<100)	1.18 (0.30-4.75)	0.81
Hypovascularity	1.78 (0.42-7.49)	0.43
Absence of washout	1.09 (0.38-3.12)	0.87
Multivariate analysis
Hispanic (versus Caucasian)	3.86 (1.02-14.65)	0.047
Alcohol (versus HCV)	6.52 (1.34-31.66)	0.02
HBV (versus HCV)	0.09 (0.01-0.93)	0.04

^*Defined as>1 cm increase in total tumor diameter over 3 months.