Skip to main content
. 2016 Jan 22;27(4):648–653. doi: 10.1093/annonc/mdw020

Table 1.

Efficacy as a function of best PET response

Efficacy nab-P + Gem
Gem
PET response
RRR or HRa (95% CI) P value PET response
RRR or HRa (95% CI) P value
Yes (N = 93) No (N = 37) Yes (N = 67) No (N = 60)
ORR by RECIST 37% 16% 2.3 (1.03–4.92) 0.023 18% 3% 5.4 (1.25–23.04) 0.009
Median PFS 7.5 months 5.3 months 0.63 (0.36–1.11) 0.110 5.6 months 3.6 months 0.39 (0.24–0.66) <0.001
Median OS 11.5 months 8.0 months 0.85 (0.54–1.32) 0.464 10.9 months 6.3 months 0.43 (0.29–0.65) <0.001

aRRR = ORRPET response/ORRno PET response; HR = HRPET response/no PET response.

Gem, gemcitabine; HR, hazard ratio; nab-P, nab-paclitaxel; ORR, overall response rate; OS, overall survival; PET, positron emission tomography; PFS, progression-free survival; RECIST, Response Evaluation Criteria In Solid Tumors; RRR, response rate ratio.