Table II. Outcomes.
Diagnosis | Good CR*† | CR | CRi | Refractory | TRM* | Relapse | HCT |
---|---|---|---|---|---|---|---|
All patients (24) | 12 (50%) | 15 (63%) | 2 (8%) | 5 (21%) | 2 (8%) | 5 (21%) | 11 (46%) |
AML (21); n (%) | 10 (48%) | 13 (62%) | 1 (5%) | 5 (24%) | 2 (9%) | 4 (19%) | 9 (43%) |
Risk groups‡ | |||||||
Favorable (4) | 3 | 0 | 0 | 0 | 1 | 0 | 0 |
Intermediate-I (4) | 3 | 1 | 0 | 0 | 0 | 1 | 3 |
Intermediate-II (6) | 2 | 1 | 1 | 1 | 1 | 2 | 2 |
Adverse (7) | 2 | 1 | 0 | 4 | 0 | 3 | 4 |
MDS (2) | 2 (100%) | 2(100%) | 0 | 0 | 1 (50%) | 1 (50%) | |
CMML (1) | 0 | 0 | 1 (100%) | 0 | 0 | 0 | 1 (100%) |
Primary study endpoints ;
CR without evidence of MRD ;
per ELN criteria ; MRD: minimal residual disease, TRM: treatment-related mortality, HCT: hematopoietic stem cell transplantation