Figure 1. Nasal and pharyngeal EPX levels represent diagnostic metrics that significantly correlate with the lower airway eosinophilia observed in poorly controlled asthmatics.

(A) The presence of sputum eosinophils stratifies asthma from control subjects. (B) EPX levels in sputum as well as the mucosal surfaces of the nasal and pharyngeal cavities of asthma patients are each statistically different between asthma and control subjects. (C) Spearman correlation demonstrates that both nasal and pharyngeal EPX assessments increase as a function of induced sputum eosinophilia.