Table 2. Relationship between Development of Diabetes and Clinical Parameters.
| Variable | Univariate analysis | Model 1 | Model 2 |
|---|---|---|---|
| Age, yr | 0.974 (0.941-1.009) | ||
| Female sex | 1.467 (0.817-2.634) | ||
| Waist circumference, cm | 1.055 (1.017-1.095) | 1.093 (1.001-1.193) | 1.046 (0.999-1.095) |
| BMI, kg/m2 | 1.114 (1.004-1.236) | 0.812 (0.630-1.036) | |
| SBP, mm Hg | 1.041 (1.020-1.062) | 0.995 (0.959-1.033) | |
| DBP, mm Hg | 1.101 (1.060-1.143) | 1.104 (1.033-1.179) | 1.096 (1.049-1.145) |
| Fasting glucose, mmol/L | 1.106 (1.060-1.154) | 1.114 (1.035-1.198) | 1.104 (1.050-1.162) |
| Fasting insulin, pmol/L | 1.014 (0.982-1.047) | ||
| Glucose, PP2, mmol/La | 1.026 (1.010-1.042) | 1.016 (0.996-1.036) | |
| Insulin, PP2, pmol/La | 1.005 (0.990-1.019) | ||
| Hemoglobin A1c, % | 6.605 (2.842-15.347) | 5.314 (1.870-15.098) | 4.662 (1.789-12.145) |
| Total cholesterol, mmol/L | 1.004 (0.994-1.014) | ||
| Triglyceride, mmol/L | 1.004 (1.000-1.007) | 1.002 (0.997-1.007) | |
| LDL-C, mmol/L | 1.001 (0.991-1.011) | ||
| HDL-C, mmol/L | 0.972 (0.940-1.006) | ||
| Albumin, g/L | 3.823 (0.631-23.182) | ||
| HOMA-B | 0.999 (0.998-1.001) | ||
| HOMA-IR | 1.095 (0.937-1.280) | ||
| Total GLP-1, pmol/L | 0.936 (0.845-1.037) | 0.954 (0.839-1.086) | 0.941 (0.833-1.063) |
| Total GIP, pmol/L | 1.004 (1.000-1.007) | 1.003 (0.998-1.008) | 1.005 (1.000-1.010) |
| Family history of DM, yes/no | 5.874 (1.468-23.494) | 2.110 (0.330-13.472) |
Values are expressed as odds ratio (95% confidence interval).
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; PP2, postprandial 2 hours; LDL-C, low density lipoprotein cholesterol; HDL-C, high density lipoprotein cholesterol; HOMA-B, homeostasis model of assessment-β cell function; HOMA-IR, homeostasis model of assessment-insulin resistance; GLP-1, glucagon-like peptide-1; GIP, glucose-dependent insulinotropic peptide; DM, diabetes mellitus.
aAccording to the method section, it should be 2-hour plasma glucose during 75 g oral glucose tolerance test. Or, the authors should mention that they performed postprandial measures, too.