Table 3. Relationship between Serum Incretin Levels and Development of Diabetes.
| 1st | 2nd | 3rd | 4th | 5th | |
|---|---|---|---|---|---|
| GLP-1 quintile | |||||
| Model 1a | 1.00 | 1.34 (0.56-3.21) | 1.11 (0.45-2.77) | 0.94 (0.36-2.45) | 0.65 (0.24-1.74) |
| Model 2b | 1.00 | 1.57 (0.64-3.87) | 1.41 (0.54-3.65) | 1.22 (0.45-3.32) | 0.89 (0.32-2.52) |
| Model 3c | 1.00 | 2.05 (0.76-5.55) | 1.80 (0.64-5.08) | 1.38 (0.47-4.01) | 0.79 (0.26-2.41) |
| GIP quintile | |||||
| Model 1a | 1.00 | 1.51 (0.54-4.24) | 1.84 (0.67-5.05) | 2.34 (0.88-6.26) | 2.89 (1.08-7.75)d |
| Model 2b | 1.00 | 1.53 (0.52-4.45) | 2.13 (0.75-6.06) | 2.74 (0.99-7.55) | 3.64 (1.30-10.20)d |
| Model 3c | 1.00 | 1.60 (0.52-4.94) | 2.31 (0.76-6.99) | 2.52 (0.87-7.31) | 3.82 (1.26-11.54)d |
Values are expressed as odds ratio (95% confidence interval).
GLP-1, glucagon-like peptide-1; GIP, glucose-dependent insulinotropic peptide.
aModel 1: unadjusted; bModel 2: age, sex, body mass index (BMI) adjusted; cModel 3: age, sex, BMI, hemoglobin A1c adjusted; dP<0