. Author manuscript; available in PMC: 2017 Apr 1.

Published in final edited form as: J Intern Med. 2015 Dec 20;279(4):376–387. doi: 10.1111/joim.12453

Table 2.

Association between physical (PCS) and mental component summary (MCS) scores and alcohol consumption 2 years later in the Nurses’ Health Study II

Outcome	Quintiles of PCS score
Outcome	Q1 (8–46)	Q2 (47–52)	Q3 (53–55)	Q4 (56–58)	Q5 (59–75)
Alcohol intake (g/day)
Unadjusted for previous alcohol intake (n_obs = 178,849; n_women = 84,621)
Lifestyle-adjusted model^a	0.00 (referent)	0.32 (0.05)^*	0.53 (0.05)^*	0.63 (0.05)^*	0.61 (0.06)^*
Morbidity-adjusted model^b	0.00 (referent)	0.31 (0.05)^*	0.51 (0.05)^*	0.62 (0.05)^*	0.61 (0.06)^*
Diet-adjusted model^c	0.00 (referent)	0.30 (0.05)^*	0.50 (0.05)^*	0.60 (0.05)^*	0.58 (0.06)^*
Adjusted for previous alcohol intake (n_obs = 165,693; n_women = 77,479)
Lifestyle-adjusted model^a	0.00 (referent)	0.23 (0.04)^*	0.38 (0.04)^*	0.48 (0.04)^*	0.55 (0.05)^*
Morbidity-adjusted model^b	0.00 (referent)	0.23 (0.04)^*	0.38 (0.04)^*	0.49 (0.05)^*	0.57 (0.05)^*
Diet-adjusted model^c	0.00 (referent)	0.22 (0.04)^*	0.37 (0.04)^*	0.47 (0.05)^*	0.53 (0.05)^*

	Quintiles of MCS score
Outcome	Q1 (0–42)	Q2 (43–49)	Q3 (50–53)	Q4 (54–56)	Q5 (57–71)

Alcohol intake (g/day)
Unadjusted for previous alcohol intake (n_obs = 178,849; n_women = 84,621)
Lifestyle-adjusted model^a	0.00 (referent)	0.00 (0.05)	-0.02 (0.05)	-0.05 (0.05)	-0.03 (0.06)
Morbidity-adjusted model^b	0.00 (referent)	0.01 (0.05)	-0.01 (0.05)	-0.03 (0.05)	0.00 (0.06)
Diet-adjusted model^c	0.00 (referent)	0.00 (0.05)	-0.02 (0.05)	-0.05 (0.05)	-0.03 (0.06)
Adjusted for previous alcohol intake (n_obs = 165,693; n_women = 77,479)
Lifestyle-adjusted model^a	0.00 (referent)	0.02 (0.05)	0.01 (0.04)	0.04 (0.04)	0.04 (0.05)
Morbidity-adjusted model^b	0.00 (referent)	0.03 (0.05)	0.03 (0.05)	0.07 (0.05)	0.07 (0.05)
Diet-adjusted model^c	0.00 (referent)	0.02 (0.05)	0.02 (0.05)	0.04 (0.05)	0.03 (0.05)

Mean difference, i.e.β-coefficient (SE), in PCS and MCS between the alcohol consumption category and the reference category.

P < 0.001.

Lifestyle-adjusted model: adjusted for time, age, physical activity, energy intake, body mass index, smoking, marital status, employment status, night shift work, race, region, living arrangement, and parity.

Morbidity-adjusted model: lifestyle-adjusted model and additionally adjusted for arthritis (osteoarthritis and rheumatoid arthritis), diabetes mellitus, hypertension, hypercholesterolemia, asthma, premenstrual syndrome, use of antidepressants, anxiolytics, analgesics, and oral contraceptives, and menopausal status.

Diet-adjusted model: morbidity-adjusted model and additionally adjusted for Alternative Healthy Eating Index-2010 without alcohol and consumption of sweetened beverages and candy.