Table 1. Clinical characteristics and baseline immune parameters.
HIV-(n = 16) | HIV+/ART treated (n = 26) |
P value | |
---|---|---|---|
Age | 38 (33-55) | 43 (32-51) | 0.87 |
Sex (male/female) | 5/16 (31.3%) | 17/26 (65.4%) | 0.07 |
CD4+ T cell counts | 771 (544-977) | 540 (366-722) | 0.03 |
%annexin V+ CD4 | 19.0 (13.0-40.0) | 30.3 (19.8-38.5) | 0.2 |
%CD38+ mCD4 | 14.3 (10.1-16.8) | 18.4 (11.3-22.9) | 0.33 |
%B cells in PBMC | 7.7 (6.2-9.5) | 9.3 (6.9-11.3) | 0.25 |
16S rDNA (copie/μL) | 5.3 (0-34.7) | 18.2 (9.4-25.2) | 0.18 |
Co-infection with HCV | 2/26 | ||
Infection duration | |||
2-5 years | 5/26 | ||
5-10 years | 3/26 | ||
> 10 years | 18/26 | ||
AIDS-defining events | |||
HIV associated malignancy | 2/26 | ||
Opportunistic infections | 4/26 | ||
Nadir CD4+ T cell counts | 294 (193-458) | ||
NNRTI based therapy | 16/26 | ||
PI based therapy | 10/26 |
Data are medians (interquartile ranges)
P value: comparisons of P value between controls and patients on D0