Table 4. Incidence (per 100 person-years) of Major Hemorrhage by CYP4F2 genotype.

CYP4F2 genotype	N	Events	FU years	Incidence	Incidence rate ratio	P Value
All
*1/*1	784	92	1099.5	8.37 (6.75 -10.26)	Reference	—
*1/*3	390	44	554.6	7.93 (5.76-10.65)	0.95 (0.66 -13.53)	0.85
*3/*3	64	4	107.5	3.72 (1.00-9.53)	0.44 (0.14-1.10)	0.09
European Americans
*1/*1	340	36	504.0	7.14 (5.00-9.89)	Reference	—
*1/*3	305	35	438.2	7.99 (5.56-11.11)	1.12 (0.70-1.79)	0.64
*3/*3	62	4	103.8	3.85 (1.04-9.87)	0.54 (0.16-1.40)	0.24
African Americans
*1/*1	444	56	595.5	9.40 (7.10-12.21)	Reference
*1/*3	85	9	116.4	7.73 (3.53-14.68)	0.82 (0.38-1.61)	0.61
*3/*3	2	0	3.7	—	—	—
CYP4F2 genotype (*1/*1 or *1/*3 versus *3/*3)
All
*1/*1 or *1/*3	1174	136	1654.1	8.22 (6.89 -9.73)	Reference	—
*3/*3	64	4	107.5	3.72 (1.00-9.53)	0.45 (0.14-1.11)	0.09
European Americans
*1/*1 or *1/*3	645	71	942.2	7.54 (5.89-9.51)	Reference	—
*3/*3	62	4	103.8	3.85 (1.04-9.87)	0.51 (0.16-1.28)	0.22
African Americans
*1/*1 or *1/*3	529	65	711.9	9.13 (7.10-11.56)	—	—
*3/*3	2	0	3.7	—	—	—
CYP4F2 genotype (*1/*1 versus *1/*3 or *3/*3)
All
*1/*1	784	92	1099.5	8.37 (6.75 -10.26)	Reference	—
*1/*3 or *3/*3	454	48	662.1	7.25 (5.35-9.61)	0.87 (0.61-1.22)	0.42
European Americans
*1/*1	340	36	504.0	7.14 (5.00-9.89)	Reference	—
*1/*3 or *3/*3	367	39	542.0	7.20 (5.12-9.84)	1.01 (0.64-1.59)	0.98
African Americans
*1/*1	444	56	595.5	9.40 (7.10-12.21)	Reference	—
*1/*3 or *3/*3	87	9	120.1	7.49 (3.42-14.23)	0.80 (0.37-1.56)	0.55

FU years: Follow-up years