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. Author manuscript; available in PMC: 2017 Mar 3.
Published in final edited form as: J Clin Periodontol. 2016 Mar 3;43(3):238–249. doi: 10.1111/jcpe.12507

Figure 1. Cp40 decreases inflammatory clinical parameters of naturally occurring chronic periodontitis in NHPs after local administration three times weekly.

Figure 1

Cp40 was injected – three times weekly for 6 weeks – into the interdental papillae and the distal gingiva of the second molars of the maxilla (“Cp40”), whereas the mandible was not treated (“Untreated”). Each animal was clinically examined at the indicated time points and the following clinical parameters were recorded: (A) gingival index; (B) bleeding on probing; (C) probing pocket depth; (D) clinical attachment level; (E) mobility index; and (F) plaque index. The data were expressed relative to the baseline values (at week 0), set as 100 (Raw data are shown for each animal in supplementary figures S1 to S10). Results are means ± SD (n =10 monkeys). *P < 0.05 and **P < 0.01 compared to baseline (one-way repeated-measures ANOVA and Bonferroni’s multiple comparisons test).