Skip to main content
. Author manuscript; available in PMC: 2017 Mar 3.
Published in final edited form as: J Clin Periodontol. 2016 Mar 3;43(3):238–249. doi: 10.1111/jcpe.12507

Figure 7. Decreased numbers of osteoclasts after treatment of natural NHP periodontitis with Cp40.

Figure 7

At the indicated time-points, alveolar bone biopsies were obtained from monkeys with natural periodontitis. The animals were treated three times (A) or once (B) weekly for 6 weeks with Cp40 in the maxilla but not in the mandible (“Untreated”). TRAP-positive multinucleated cells (osteoclasts) were enumerated in 10 randomly selected sections for each bone biopsy specimen from the maxilla or mandible of each of the animals. The numbers of osteoclasts were averaged for each biopsy specimen and are represented by dots. Scatter dot plots with mean ± SD are shown for each group of monkeys (A, n = 10; B, n = 5 animals). Indicated P values determined by one-way repeated-measures ANOVA and Tukey’s multiple comparisons test.