Figure 5.
JNK1 is required for miR-203 expression and down-regulated at the protein level in galectin-7 knockdown cells. (a and b) The knockdown of JNK1 and p63 mRNA levels. (c and d) Expression of miR-203 in HaCaT cells with a transient knockdown of either JNK1 or p63. (e) The relative mRNA levels of JNK1 in galectin-7 knockdown cells. (f) The protein levels of JNK1 in galectin-7 knockdown cells. The relative fold changes of JNK1, p63, and miR-203 in JNK1 and p63 knockdown HaCaT cells were normalized to the empty-vector control. The statistical analyses were performed by individually comparing with the HaCaT parental cell line (P), ns: not significant, ***P < 0.001.