Table 4.

Association between FTND items, FTND score, and rs3743078, in lifetime smokers (n = 662)

FTND item	Association of FTND item with rs3743078 risk factora: OR [95% CI]	Association of total FTND score with rs3743078 risk factorb: Regression coefficient OR [95% CI]
Smoking just/shortly after getting up in the morningc	2.14 [1.11, 4.15]*	0.43 [0.01, 0.85]*
Difficulty refraining when smoking was not allowed	2.25 [1.23, 4.14]**	0.53 [-0.04, 1.10]
Smoking more frequently in the morning	3.71 [0.88, 15.58]	0.68 [0.07, 1.29]*
Smoking even when ill in bed	1.02 [0.52, 2.00]	1.04 [0.50, 1.58]***

Notes: Categorical cigarettes per day (CPD) is a Fagerström Test of Nicotine Dependence (FTND) item, but it was not included in this table because indirect effects were evaluated for continuous CPD. OR = odds ratio; CI = confidence interval.

^aFrom logistic regression, adjusting for sex, age, ethnicity.

^bFrom linear regression, adjusting for sex, age, and ethnicity, as well as the FTND item.

^cProxy for “How soon after waking do you smoke your first cigarette?”

^*p < .05;

^**p < .01;

^***p < .0001.