Table 2.
Germline mutation | Somatic mutation | |
---|---|---|
Gene | APC | TP53 |
Codon | 1309 | 237 |
Reference allele | T | G |
Alternative allele (AA) | -AAAAG | A |
Coverage in the wild type (WT) | 2022 | 1728 |
AA frequency in the WT | 48.22% | 0.00% |
Coverage in the patient sample | 1271 | 872 |
AA frequency in the patient sample | 68.61% | 12.96% |
P-value | 0 | 1.45E-56 |
Adjusted P-value | 0 | 4.98E-54 |