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Experiment 2: mutations found in the DNA samples extracted from 37 y/o patient diagnosed with adenocarcinoma.
| Germline mutation | Somatic mutation | |
|---|---|---|
| Gene | APC | TP53 |
| Codon | 1309 | 237 |
| Reference allele | T | G |
| Alternative allele (AA) | -AAAAG | A |
| Coverage in the wild type (WT) | 2022 | 1728 |
| AA frequency in the WT | 48.22% | 0.00% |
| Coverage in the patient sample | 1271 | 872 |
| AA frequency in the patient sample | 68.61% | 12.96% |
| P-value | 0 | 1.45E-56 |
| Adjusted P-value | 0 | 4.98E-54 |
