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Experiment 3: mutations found in the DNA samples extracted from patient 2.
| Tumor | Stool | ||
|---|---|---|---|
| Gene | APC | APC | APC |
| Codon | 1491 | 1491 | 1556 |
| Reference allele | A | A | G |
| Alternative allele (AA) | − T | − T | + A |
| Coverage in the wild type (WT) | 7372 | 7372 | 7359 |
| AA frequency in the WT (%) | 0.00 | 0.00 | 0.04 |
| Coverage in the patient sample | 8005 | 8005 | 7984 |
| AA frequency in the patient sample (%) | 19.05 | 0.37 | 1.32 |
| P-value | 0 | 3.04E-09 | 2.72E-26 |
| Adjusted P-value | 0 | 3.43E-07 | 8.16E-24 |
