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. 2015 Nov 21;15:341–350. doi: 10.1007/s10689-015-9852-6

Table 4.

Participants’ knowledge about hereditary cancer

Statement Participants who gave correct answer (%)
If a women’s BRCA1 or BRCA2 gene result shows a variant of unknown significance, other affected family members need to be tested in order to determine the meaning of the result. (false) 41
If a woman’s BRCA1 or BRCA2 gene result reveals a positive test, she should be counseled to have her ovaries surgically removed after she is done having children. (true) 96
If a father has a mutation in the APC gene (Familial adenomatous polyposis (FAP), his children have a 50 % chance (1 in 2) for carrying this mutation as well. (true) 80
After removal of colon polyps for an FAP diagnosis regular bowel examinations are no longer necessary. (false) 91
A hereditary predisposition to FAP can skip a generation. (false) 52
If a person has colorectal cancer at age 49 and also has a family member with endometrial cancer diagnosed at age 60 years, genetic testing is indicated. (true) 84
A person with uterine cancer at 49 years of age has an indication for genetic counseling. (true) 57
A person with two melanomas has an indication for genetic counseling. (true) 72
If a female is found to have a BRCA mutation and her sister’s BRCA result is negative, the sister is still at increased risk for developing ovarian cancer. (false) 68