Figure 7.

Epithelial NF-κB Deficiency Does Not Trigger Colitis but Causes RIPK1 Kinase Dependent Paneth Cell Death

(A, F, and J) Representative images of colon and ileal sections from mice with the indicated genotypes.

(B, G, and K) Graphs depicting histopathological scores of colon and ileal sections from mice with the indicated genotypes (n = 5–18 mice per genotype).

(C, H, and L) Graphs depicting the percentage of crypts with cl. casp. 3 stained cells on colon and ileal sections from littermates with the indicated genotypes (n = 4–12 mice per genotype).

(D and M) Graphs depicting Paneth cell scores of ileal sections from mice with the indicated genotypes (n = 4–12 mice per genotype).

(E, I, and N) Graphs depicting mRNA levels of the indicated genes in the colon and ileum of mice with the indicated genotypes (n = 5–12 mice per genotype).

Scale bars represent 100 μm. See also Figures S5 and S6.