Table 4.
Parameter (unit) | BMI group | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Decreased BMI | p-valuea | Stable BMI | p-valuea | Increased BMI | p-valuea | |||||||||||||
2006 | 2011 | 2006 | 2011 | 2006 | 2011 | |||||||||||||
N | Mean | SD | Mean | SD | N | Mean | SD | Mean | SD | N | Mean | SD | Mean | SD | ||||
Men | ||||||||||||||||||
SBP (mm Hg) | 2319 | 127•0 | 15•6 | 120•5 | 15•0 | <0•0001b | 10461 | 122•7 | 14•2 | 120•4 | 14•8 | <0•0001 | 3860 | 121•3 | 13•4 | 121•9 | 13•9 | 0•005c |
DBP (mm Hg) | 2319 | 78•9 | 10•8 | 74•9 | 11•5 | <0•0001 | 10461 | 75•8 | 10•1 | 74•7 | 11•1 | <0•0001 | 3860 | 74•4 | 10•1 | 75•8 | 11•3 | <0•0001 |
HDL-C (mmol/l) | 2221 | 1•4 | 0•3 | 1•6 | 0•4 | <0•0001 | 10087 | 1•5 | 0•4 | 1•6 | 0•4 | <0•0001 | 3750 | 1•4 | 0•3 | 1•4 | 0•3 | <0•0001 |
LDL-C (mmol/l) | 2188 | 3•3 | 0•9 | 3•0 | 0•8 | <0•0001 | 9928 | 3•1 | 0•8 | 3•1 | 0•8 | <0•0001 | 3693 | 3•1 | 0•8 | 3•3 | 0•8 | <0•0001 |
TG (mmol/l) | 1597 | 1•6 | 1•1 | 1•2 | 0•8 | <0•0001 | 7039 | 1•4 | 1•1 | 1•4 | 1•0 | n.s. | 2364 | 1•3 | 1•3 | 1•6 | 1•3 | <0•0001 |
FBG (mmol/l) | 1489 | 5•4 | 1•0 | 5•4 | 1•5 | n.s. | 6733 | 5•2 | 0•6 | 5•2 | 0•8 | <0•0001 | 2243 | 5•1 | 0•5 | 5•2 | 0•6 | <0•0001 |
HbA1c (%) | 764 | 5•72 | 0•88 | 5•75 | 1•01 | n.s. | 3085 | 5•47 | 0•63 | 5•58 | 0•65 | <0•0001 | 883 | 5•43 | 0•69 | 5•61 | 0•64 | <0•0001 |
Women | ||||||||||||||||||
SBP (mm Hg) | 1483 | 119•1 | 16•3 | 113•8 | 16•6 | <0•0001 | 6604 | 114•9 | 14•8 | 112•7 | 15•4 | <0•0001 | 2097 | 113•6 | 14•4 | 114•3 | 14•8 | 0•023 |
DBP (mm Hg) | 1483 | 72•1 | 10•5 | 68•6 | 10•9 | <0•0001 | 6604 | 70•1 | 9•5 | 68•1 | 10•9 | <0•0001 | 2097 | 69•6 | 9•6 | 69•6 | 11•2 | n.s. |
HDL-C (mmol/l) | 1342 | 1•7 | 0•4 | 1•9 | 0•4 | <0•0001 | 6164 | 1•7 | 0•3 | 1•8 | 0•4 | <0•0001 | 1991 | 1•7 | 0•3 | 1•8 | 0•4 | <0•0001 |
LDL-C (mmol/l) | 1330 | 3•3 | 0•8 | 3•0 | 0•8 | <0•0001 | 6106 | 3•1 | 0•8 | 3•0 | 0•8 | <0•0001 | 1961 | 3•0 | 0•8 | 3•1 | 0•8 | <0•0001 |
TG (mmol/l) | 1024 | 1•0 | 0•6 | 0•8 | 0•5 | <0•0001 | 4799 | 0•8 | 0•5 | 0•9 | 0•5 | <0•0001 | 1515 | 0•8 | 0•5 | 1•0 | 0•6 | <0•0001 |
FBG (mmol/l) | 1052 | 5•1 | 0•7 | 5•0 | 1•1 | <0•0001 | 4854 | 5•0 | 0•5 | 5•0 | 0•5 | <0•0001 | 1477 | 5•0 | 0•4 | 5•0 | 0•5 | <0•0001 |
HbA1c (%) | 592 | 5•64 | 0•67 | 5•65 | 0•65 | n.s. | 2341 | 5•50 | 0•40 | 5•58 | 0•44 | <0•0001 | 586 | 5•43 | 0•45 | 5•55 | 0•42 | <0•0001 |
Note. N: number of subjects after selection criteria were applied; SD: standard deviation; BMI: body mass index (kg/m2); SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; TG: triglycerides; HbA1c: hemoglobin A1c; FBG: fasting blood glucose; decreased BMI: ΔΔBMI ≥-1.1; stable BMI: ΔBMI -1.1–1.1; increased BMI: ΔBMI ≥ 1.1; ΔBMI = 2011 BMI – 2006 BMI;
Paired t-test was used to analyze significant differences between mean serum parameter values in 2006 and 2011;
blue highlighting indicates a significant decrease in the mean serum parameter value;
orange highlighting indicates a significant increase in the mean serum parameter value; n.s., not significant