Table 2.

TBOA has a greater effect on astrocyte basal iGluSnFR signals in WT mice than in R6/2 mice

	Baseline dF/F	+ TBOA dF/F	p	Fold-change from baseline to TBOA	n (cells, mice)
WT	0.01 ± 0.01	0.39 ± 0.04	<0.00001	39.8 ± 10.2	19, 4
R6/2	0.03 ± 0.01	0.16 ± 0.03	<0.00001	7.7 ± 2.5	24, 4

Data are from experiments such as those illustrated in Figure 7B, but summarized here for R6/2 and noncarrier controls (WT). TBOA significantly increased the iGluSnFR signals in WT and R6/2 mice, but the fold changes were significantly greater in WT (p < 0.00001). The mean values for fold changes calculated from individual experiments are shown.