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. 2016 Mar 9;2016:2839697. doi: 10.1155/2016/2839697

Table 2.

Frequency of MMP-2 (-1306 C/T) genotype in the patients with pituitary adenoma (PA) and in the control group.

Gene marker Genotype/allele Frequency (%)
Control group
n (%)
(n = 318)
p
HWE
PA group
n (%)
(n = 84)
p
HWE
p value
MMP-2 (-1306) Rs243865 Genotype 0.383 0.390
 C/C 190 (59.75) 42 (50.00) χ 2 = 2.980 
 C/T 108 (33.96) 37 (44.00) p = 0.225
 T/T 20 (6.29) 5 (6.00)
 Total 318 (100) 84 (100)
Allele
 C 0.767 0.720
 T 0.233 0.280

MMP: matrix metalloproteinase; p value: significance level (alfa = 0.05); p-value HWE: significance level (alfa = 0.05) by Hardy-Weinberg equilibrium.