Table 1.
Characteristics of study cohort (n=238 963) at baseline. Values are numbers (percentages) unless stated otherwise
| Characteristic | Value |
|---|---|
| Female sex | 146 028 (61.1) |
| Mean (SD) age, years | 39.5 (11.1) |
| Ethnic group: | |
| Recorded | 136 624 (57.2) |
| White/not recorded | 227 451 (95.2) |
| Non-white | 11 512 (4.8) |
| Depression severity (index diagnosis): | |
| Mild | 171 208 (71.7) |
| Moderate | 59 140 (24.8) |
| Severe | 8615 (3.6) |
| Smoking status*: | |
| Non-smoker | 110 849 (47.5) |
| Ex-smoker | 35 132 (15.1) |
| Current light smoker | 24 104 (10.3) |
| Current moderate smoker | 40 546 (17.4) |
| Current heavy smoker | 22 659 (9.7) |
| Not recorded | 5673 |
| Alcohol consumption*: | |
| Non-drinker | 55 253 (27.2) |
| Trivial (<1 unit/day) | 77 579 (38.2) |
| Light (1-2 units/day) | 51 310 (25.3) |
| Moderate (3-6 units/day) | 14 482 (7.1) |
| Heavy (7-9 units/day) | 2174 (1.1) |
| Very heavy (>9 units/day) | 2391 (1.2) |
| Not recorded | 35 774 |
| Townsend deprivation score in fifths*: | |
| 1 (least deprived) | 45 021 (19.5) |
| 2 | 46 207 (20.0) |
| 3 | 48 293 (20.9) |
| 4 | 47 063 (20.4) |
| 5 (most deprived) | 44 178 (19.1) |
| Not recorded | 8201 |
| Comorbidities at baseline: | |
| Coronary heart disease | 4109 (1.7) |
| Diabetes | 7371 (3.1) |
| Hypertension | 17 217 (7.2) |
| Stroke/transient ischaemic attack | 1741 (0.7) |
| Arrhythmia | 2373 (1.0) |
| Any cancer | 3810 (1.6) |
| Asthma/chronic obstructive pulmonary disease | 31 816 (13.3) |
| Epilepsy/seizures | 3325 (1.4) |
| Hypothyroidism | 5267 (2.2) |
| Obsessive-compulsive disorder | 494 (0.2) |
| Osteoarthritis | 7228 (3.0) |
| Osteoporosis | 867 (0.4) |
| Liver disease | 698 (0.3) |
| Renal disease | 549 (0.2) |
| Rheumatoid arthritis | 1301 (0.5) |
| Drugs at baseline: | |
| Anticonvulsants | 2672 (1.1) |
| Antihypertensives | 25 344 (10.6) |
| Antipsychotics | 836 (0.4) |
| Anticoagulants | 1073 (0.5) |
| Aspirin | 7159 (3.0) |
| Bisphosphonates | 854 (0.4) |
| Hypnotics/anxiolytics | 11 354 (4.8) |
| Non-steroidal anti-inflammatory drugs | 12 725 (5.3) |
| Statins | 10 823 (4.5) |
| Oral contraceptives† | 27 396 (18.8) |
| Hormone replacement therapy† | 7207 (4.9) |
*Percentages are out of total with recorded values.
†Percentage is for females only.