Table 2. Pooled outcomes of all the subgroups.
| Outcomes | No. of Studies | No. of cases: Barbed/Control | SMD/MD/OR | 95%CI | Heterogeneity: | P value for effect size |
|---|---|---|---|---|---|---|
| SUTURE TIME | ||||||
| Laparoscopic myomectomy¶ | 2 | 58/103 | −5.50 | [−7.03, −3.96] | P = 0.66; I2 = 0% | Z = 7.04 (P < 0.00001) |
| Laparoscopic hysterectomy¶ | 2 | 50/74 | −1.10 | [−4.52, 2.32] | P = 0.02; I2 = 83% | Z = 0.63 (P = 0.53) |
| Arthroplasty¶ | 3 | 259/269 | −0.66 | [−4.43, 3.11] | P < 0.00001; I2 = 97% | Z = 0.34 (P = 0.73) |
| Cosmetic surgery¶ | 2 | 259/259 | −6.76 | [−8.72, −4.79] | P= 0.25; I2 = 25% | Z = 6.73 (P < 0.00001) |
| Sacrocolpopexy¶ | 1 | 32/32 | −13.60 | [−20.63, −6.57] | N/A | Z = 3.79 (P = 0.0001) |
| Gastric bypass¶ | 1 | 30/30 | −11.30 | [−12.23, −10.37] | N/A | Z =23.73 (P < 0.00001) |
| Robot-assisted laparoscopic prostatectomy¶ | 1 | 45/36 | −0.10 | [−0.19, −0.01] | N/A | Z = 2.24 (P = 0.03) |
| Cesarean delivery¶ | 1 | 127/61 | 0.60 | [−0.30, 1.50] | N/A | Z = 1.31 (P = 0.19) |
| Unidirectional barbed§ | 5 | 356/347 | −1.75 | [−2.69, −0.81] | P < 0.00001; I2 = 95% | Z = 3.65 (P = 0.0003) |
| Bidirectional barbed§ | 7 | 454/467 | −0.28 | [−0.89, 0.32] | P < 0.00001; I2 = 94% | Z = 0.92 (P = 0.36) |
| OPERATIVE TIME | ||||||
| Robot-assisted laparoscopic prostatectomy¶ | 2 | 76/69 | −6.85 | [−14.87, 1.17] | P = 0.90; I2 = 0% | Z = 1.68 (P = 0.09) |
| Laparoscopic myomectomy¶ | 2 | 58/103 | −2.73 | [−5.32, −0.14] | P = 0.43; I2 = 0% | Z = 2.07 (P = 0.04) |
| Laparoscopic hysterectomy¶ | 2 | 50/74 | −4.48 | [−13.40, 4.43] | P = 0.31; I2 = 3% | Z = 0.32 (P = 0.99) |
| Gastric bypass¶ | 1 | 30/30 | −11.70 | [−22.83, −0.57] | N/A | Z = 2.06 (P = 0.04) |
| Unidirectional barbed§ | 4 | 128/121 | −0.35 | [−0.60, −0.09] | P = 0.85; I2 = 0% | Z = 2.70 (P = 0.007) |
| Bidirectional barbed§ | 3 | 86/155 | −0.20 | [−0.55, 0.16] | P = 0.19; I2 = 39% | Z = 1.09 (P = 0.28) |
| ESTIMATE THE INTRAOPERATIVE BLOOD LOSS | ||||||
| Robot-assisted laparoscopic prostatectomy§ | 2 | 78/69 | 0.03 | [−0.29, 0.36] | P = 0.55; I2 = 0% | Z = 0.19 (P = 0.85) |
| Laparoscopic myomectomy§ | 1 | 22/22 | −0.83 | [−1.45, −0.21] | N/A | Z = 2.64 (P = 0.008) |
| Laparoscopic hysterectomy§ | 1 | 32/31 | 0.31 | [−0.18, 0.81] | N/A | Z = 1.23 (P = 0.22) |
| Unidirectional barbed§ | 3 | 100/91 | −0.22 | [−0.74, 0.29] | P = 0.04; I2 = 68% | Z = 0.85 (P = 0.40) |
| Bidirectional barbed§ | 1 | 32/31 | 0.31 | [−0.18, 0.81] | N/A | Z = 1.23 (P = 0.22) |
| COMPLICATIONS | ||||||
| Robot-assisted laparoscopic prostatectomy* | 3 | 109/102 | 2.79 | [0.89, 8.79] | P = 0.10; I2 = 62% | Z = 1.75 (P = 0.08) |
| Laparoscopic myomectomy* | 2 | 58/103 | N/A | N/A | N/A | N/A |
| Laparoscopic hysterectomy* | 2 | 50/74 | 0.70 | [0.24, 2.08] | N/A | Z = 0.63 (P = 0.53) |
| Cesarean delivery* | 2 | 166/100 | 0.69 | [0.34, 1.38] | P = 0.26; I2 = 20% | Z = 1.05 (P = 0.29) |
| Arthroplasty* | 4 | 290/298 | 1.19 | [0.58, 2.41] | P = 0.12; I2 = 48% | Z = 0.48 (P = 0.63) |
| Cosmetic surgery* | 2 | 259/259 | 2.47 | [1.50, 4.06] | P = 0.01; I2 = 83% | Z = 3.56 (P = 0.0004) |
| Gastric bypass* | 1 | 30/30 | 0.50 | [0.05, 5.02] | N/A | Z = 0.59 (P = 0.56) |
| Sacrocolpopexy* | 1 | 32/32 | 1.53 | [0.25, 9.38] | N/A | Z = 0.46 (P = 0.64) |
| Unidirectional barbed* | 7 | 428/419 | 2.13 | [1.35, 3.35] | P = 0.007; I2 = 72% | Z = 3.25 (P = 0.001) |
| Bidirectional barbed* | 9 | 516/529 | 0.96 | [0.61, 1.50] | P=0.63; I2 = 0% | Z = 0.17 (P = 0.86) |
¶MD= mean difference.
§SMD=standardized mean difference.
*OR=Odds ratio.
NA: Not applicable.