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| Phenotype | Sample ID | Total | Wild type | In-frame indels |
Frame-shift indels | Null mutation (%) | |
|---|---|---|---|---|---|---|---|
| Conserved aa not affected | Conserved aa affected | ||||||
| WT-like | W1 | 18 | 8 | 0 | 7 | 3 | 55.6 |
| W2 | 20 | 9 | 0 | 5 | 6 | 55.0 | |
| W3 | 19 | 13 | 0 | 4 | 2 | 31.6 | |
| Heart disorder | H1 | 20 | 4 | 0 | 9 | 7 | 80.0 |
| H2 | 19 | 1 | 0 | 10 | 8 | 94.7 | |
| H3 | 17 | 4 | 0 | 8 | 5 | 76.5 | |
Total, the total number of valid sequence analysed; WT-like, wild type-like; aa, amino acid.
