Table 5.
Regions identified as hubs in the networks of healthy controls and MDD patients
| HC | MDD | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Regions | Average b (i) | Regions | Average S (i) | Regions | Average b (i) | Regions | Average S (i) | ||||
| PCUN | Left | 4.24 | PUT | Left | 4.73 | PCUN | Left | 4.27 | CAU | Left | 4.37 |
| PCUN | Right | 4.11 | PCUN | Left | 4.57 | PCUN | Right | 3.47 | PCUN | Right | 4.31 |
| CAL | Left | 3.14 | CAU | Left | 4.37 | OLF | Left | 3.12 | PCUN | Left | 4.18 |
| LING | Right | 2.91 | PCUN | Right | 4.35 | DCG | Right | 2.88 | PUT | Left | 3.98 |
| DCG | Right | 2.70 | HIP | Left | 4.15 | OLF | Right | 2.35 | HIP | Left | 3.96 |
| LING | Left | 2.62 | PUT | Right | 4.08 | INS | Left | 2.32 | PUT | Right | 3.75 |
| DCG | Left | 2.38 | SOG | Right | 3.95 | CAL | Left | 2.16 | CAL | Right | 3.73 |
| OLF | Left | 2.21 | MOG | Right | 3.86 | DCG | Left | 2.11 | SOG | Right | 3.72 |
| INS | Right | 2.19 | MOG | Left | 3.84 | IFGorb | Right | 2.04 | INS | Right | 3.62 |
| ACG | Left | 2.19 | CAL | Right | 3.82 | STG | Right | 1.93 | CAL | Left | 3.55 |
| CAL | Right | 2.09 | INS | Right | 3.79 | LING | Left | 1.90 | ACG | Left | 3.51 |
| OLF | Right | 1.98 | CAL | Left | 3.76 | INS | Right | 1.84 | MOG | Left | 3.32 |
| INS | Left | 1.89 | PreCG | Left | 3.61 | INS | Left | 3.29 | |||
| PreCG | Right | 3.54 | PosCG | Right | 3.29 | ||||||
| STG | Right | 3.49 | DCG | Left | 3.17 | ||||||
| INS | Left | 3.48 | |||||||||
| CAU | Right | 3.45 | |||||||||
| DCG | Left | 3.44 | |||||||||
b (i): The normalized nodal betweenness; S (i): The nodal strength. The regions in bold font were the hubs that identified by both b (i) and S (i). PreCG: Precentral gyrus; PosCG: Postcentral gyrus; IFGorb: Inferior frontal gyrus, orbital; OLF: Olfactory cortex; STG: Superior temporal gyrus; PCUN: Precuneus; CAL: Calcarine fissure and surrounding cortex; LING: Lingual gyrus; SOG: Superior occipital gyrus; MOG: Middle occipital gyrus; ACG: Anterior cingulate and paracingulate gyri; DCG: Median cingulate and paracingulate gyri; INS: Insula; PUT: Lenticular nucleus, putamen; CAU: Caudate nucleus; HIP: Hippocampus; HC: Healthy controls; MDD: Major depressive disorder.