Table 3.
Increased brain activation from whole-brain studies only in CRT patients compared with non-CRT patients from pre- to post-training
| Cluster number | Volume (mm3) | Peak ALE value | Talairach coordinates | Label | Brodmann area | Contributed number of foci | ||
|---|---|---|---|---|---|---|---|---|
| X | Y | Z | ||||||
| 1 | 568 | 0.010697 | 44 | 2 | 44 | Right, middle frontal gyrus | 6 | 3 |
| 2 | 552 | 0.010837 | 40 | −24 | 44 | Right, postcentral gyrus | 2 | 1 |
| 3 | 440 | 0.010826 | −6 | −8 | 70 | Left, medial frontal gyrus | 6 | 1 |
| 4 | 280 | 0.007419 | 48 | −52 | 42 | Right, inferior parietal lobule | 40 | 2 |
| 5 | 208 | 0.007155 | −54 | 8 | 34 | Left, middle frontal gyrus | 9 | 2 |
| 0.006542 | −56 | 10 | 28 | Left, inferior frontal gyrus | 9 | |||
The peak coordinates were in the Talairach system (right; left). Clusters identified in the meta-analysis were obtained after controlling the false discovery rate corrected at P<0.05 and applying a minimum cluster size of 200 mm3. CRT: Cognitive remediation therapy; ALE: Activation likelihood estimation.