Table 2.
CHR | Start (bp) | End (bp) | Length of the QTL region (bp) | Significant SNPs in region | No of genes with significant SNPs within the QTL region | Top SNP | Position of the top SNP (bp) | - log10(p) | MAF | Gene | Annotation of the top SNP | b.value | SE |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fat yield | |||||||||||||
5 | 92,372,732 | 94,425,668 | 2,052,936 | 330 | 3 | rs209818856 | 93,945,694 | 27.49 | 0.38 | MGST1 | intron variant | −2.807 | 0.253 |
14 | 1,448,510 | 2271832 | 823,322 | 509 | 49 | rs136783505 | 1,807,140 | 42.01 | 0.07 | DGAT1/HSF1 | downstream variant/intron variant | −6.709 | 0.484 |
23 | 28,567,796 | 28,591,530 | 23,734 | 5 | 1 | rs381390819 | 28,567,796 | 9.36 | 0.45 | TRIM26 | intron variant | 1.148 | 0.184 |
25 | 8,222,347 | 11,507,986 | 3,285,639 | 883 | 16 | rs379546164 | 9,870,005 | 14.40 | 0.24 | CLEC16A | intron variant | −1.769 | 0.224 |
25 | 36,226,978 | 36,227,132 | 154 | 2 | rs109480808 | 36,226,978 | 8.72 | 0.16 | intergenic variant | 1.635 | 0.272 | ||
26 | 22,144,777 | 24,793,744 | 2,648,967 | 595 | 32 | rs438420348 | 24,379,571 | 14.28 | 0.16 | NEURL1 | intron variant | −2.273 | 0.290 |
26 | 44,802,991 | 44,802,991 | 0 | 1 | rs135624939 | 44,802,991 | 9.72 | 0.28 | intergenic variant | −1.474 | 0.231 | ||
Milk yield | |||||||||||||
5 | 112,343,204 | 11,2450,860 | 107,656 | 2 | 1 | rs383553819 | 112,343,204 | 8.70 | 0.36 | MKL1 | intron variant | 1.437 | 0.239 |
14 | 1,448,510 | 2,271,832 | 823,322 | 455 | 48 | rs133033480 | 1,743,939 | 33.01 | 0.09 | CPSF1/ADCK5 | downstream variant/splice region variant, intron variant | 6.266 | 0.513 |
16 | 1,322,611 | 1,322,611 | 0 | 1 | 1 | rs108979795 | 1,322,611 | 8.58 | 0.28 | LAX1 | upstream variant | −1.451 | 0.243 |
19 | 61,447,138 | 61,449,096 | 1958 | 5 | rs210324693 | 61,449,096 | 8.93 | 0.32 | intergenic variant | 1.490 | 0.244 | ||
20 | 30,531,217 | 32,952,019 | 2,420,802 | 74 | 5 | rs385640152 | 31,909,478 | 15.56 | 0.11 | GHR | missense variant | −3.877 | 0.472 |
20 | 37,766,226 | 39,183,141 | 1,416,915 | 34 | 3 | NA | 38,828,254 | 9.54 | 0.16 | intergenic variant | −2.250 | 0.356 | |
25 | 2,669,704 | 2,669,704 | 0 | 1 | rs209691835 | 2,669,704 | 9.21 | 0.13 | intergenic variant | −2.855 | 0.460 | ||
25 | 3,494,706 | 3,516,671 | 21,965 | 13 | 4 | rs110749311 | 3,498,960 | 9.32 | 0.41 | PAM16/GLIS2 | downstream variant | 1.225 | 0.196 |
Protein yield | |||||||||||||
5 | 112,450,860 | 112,450,860 | 0 | 1 | rs109041054 | 112,450,860 | 8.88 | 0.48 | intergenic variant | −1.473 | 0.242 | ||
14 | 1,802,667 | 1,802,667 | 0 | 1 | 2 | NA | 1,802,667 | 8.52 | 0.06 | DGAT1/HSF1 | intron variant/downstream variant | 3.354 | 0.564 |
25 | 1,094,996 | 1,257,612 | 162,616 | 12 | 3 | rs136085792 | 1,103,856 | 10.83 | 0.22 | UNKL | intron variant | 1.694 | 0.250 |
25 | 3,306,363 | 3,516,671 | 210,308 | 40 | 8 | rs110749311 | 3,498,960 | 11.70 | 0.41 | PAM16/GLIS2 | downstream variant | 1.427 | 0.202 |