Table 1.
Demographic, clinical, laboratory characteristics and prevalence of VDR FokI polymorphism of T1DM patients according to presence or absence of thyroid dysfunction (TD)
| With TD | Without TD | p | |
|---|---|---|---|
| n (%) | 25 (13.9) | 155 (86.1) | |
| Gender (female %) | 72.0 | 48.4 | 0.02 |
| Age (years) | 16.8 ± 7.1 | 17.1 ± 5.0 | 0.28 |
| Age at diagnosis of diabetes (years) | 10.0 ± 4.0 | 10.2 ± 5.1 | 0.80 |
| TDDM (years) | 6.9 ± 6.3 | 6.9 ± 5.2 | 0.72 |
| Age at diagnosis of TD (years) | 13.8 ± 6.5 | – | |
| BMI (kg/m2) | 21.3 ± 3.2 | 22.0 ± 3.6 | 0.18 |
| TSH (mUI/mL) | 19.1 ± 59.0 | 2.2 ± 1.4 | 0.00 |
| TPO Ab positive (%) | 80.0 | 25.0 | <0.001 |
| GAD Ab positive (%) | 56.0 | 30.3 | 0.01 |
| IA2 Ab positive (%) | 36.0 | 43.1 | 0.50 |
| FCP (ng/mL) | 0.18 ± 0.29 | 0.19 ± 0.42 | 0.77 |
| A1c (%) | 9.3 ± 1.6 | 9.2 ± 1.8 | 0.75 |
| ff/Ff genotypes (%) | 73.9 | 52.7 | 0.05 |
Data are expressed as mean ± SD unless otherwise indicated
TDDM time of duration of diabetes, FCP fasting serum C-peptide