Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Therapeutic potential of SOF. SOF or its analogs may have therapeutic potential as agents that enhance cholesterol uptake by the liver and promote its clearance into bile. rSOF acts on HDL to form neoHDL, lipid free apo AI and CERM. The first two products promote macrophage cholesterol efflux. CERM promotes hepatocyte CE uptake by interaction with several liver receptors. After uptake, CERM-CE is metabolized and secreted as bile acids.
