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. Author manuscript; available in PMC: 2017 Mar 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Dec 18;1861(3):196–204. doi: 10.1016/j.bbalip.2015.12.006

Table 1. Kinetic Constants for HDL-, CERM-, and LDL-[¹⁴C]CE Metabolism^a.

Precursor	k_d, h^-1, (t_1/2, h)	k_r, h^-1, (max %)	m (%/h)
	[¹⁴C]CE	[¹⁴C]FC	[¹⁴C]oxysterol
HDL-[¹⁴C]CE	0.23 ± 0.01, (3.0)	0.26 ± 0.09, (78 ± 12)	1.9 ± 0.3
CERM-[¹⁴C]CE	0.15 ± 0.02, (4.4)	0.27 ± 0.03, (65 ± 3)	0.9 ± 0.5^b
LDL-[¹⁴C]CE	0.13 ± 0.02, (5.4)	0.14 ± 0.12, (72 ± 37)	2.1 ± 0.2

^a

Values are calculated kinetic constants ± SE from Figure 2 D – F, fitting the data to an exponential decay (k_d), exponential rise (k_r) or linear fit (m).

^b

Oxysterol rate of formation from CERM-CE is significantly different from LDL-CE (p=0.037) but not HDL-CE (p=0.102)