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. Author manuscript; available in PMC: 2016 Mar 23.
Published in final edited form as: Genes Brain Behav. 2014 Aug 28;13(7):579–591. doi: 10.1111/gbb.12159

Figure 8. TPH2−/− dams do not show anxiety-like behavior upon separation from their own or cross-fostered pups.

Figure 8

TPH2+/+ (WT) and TPH2−/− (KO) dams raising their own or cross-fostered pups were assessed for anxiety-like behaviors using the EPM (a–c) or the LD (d–f). Dams and pup genotypes are designated in the legend of Figure 1. In the elevated plus maze, dams were assessed for (a) time spent in the open arms, (b) time spent in the closed arms and (c) distance traveled. In the light–dark box, dams were assessed for (a) time spent in the lighted compartment, (b) time spent in the dark compartment and (f) distance traveled. Data are expressed as the mean ± SEM. *P < 0.05.