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. Author manuscript; available in PMC: 2016 May 19.
Published in final edited form as: Nature. 2015 Oct 12;527(7578):336–341. doi: 10.1038/nature15249

Extended Data Figure 3. 3D cryo-EM density map of the tetrameric InsP3R1 visualized in three orthogonal orientations.

Extended Data Figure 3

InsP3R1 viewed from the cytosol (top), along the membrane plane (middle) and from the lumen (bottom). Four individual subunits are colour-coded. The map is rendered at a threshold level corresponding to a molecular mass of ~1.3 MDa.