Table 1. Baseline characteristics of patients .
Group 1 (43) | Group 2 (124) | Group 3 (97) | p-value | |
General demographics | ||||
Age (yr) | 60.74 ± 13.35 | 58.91 ± 12.72 | 61.57 ± 12.28 | 0.289 |
Male sex (%) | 88.4 | 85.5 | 81.4 | 0.529 |
BMI | 25.36 ± 2.87 | 25.14 ± 3.24 | 24.98 ± 4.32 | 0.844 |
Risk factors for MI | ||||
Diabetes mellitus (%) | 48.8 | 36.3 | 36.1 | 0.296 |
Current smoker (%) | 62.8 | 48.4 | 40.2 | 0.171 |
Hypertension (%) | 53.5 | 59.7 | 53.6 | 0.732 |
Old MI (%) | 2.3 | 3.2 | 3.1 | 0.956 |
HF (advanced) (%) | 4.6 | 5.6 | 8.2 | 0.647 |
ESRD (%) | 2.3 | 1.6 | 3.1 | 0.764 |
Dyslipidemia (%) | 37.2 | 33.1 | 37.9 | 0.736 |
The severity of MI | ||||
SBP | 156.30 ± 30.87a | 138.00 ± 30.07b | 135.70 ± 27.00b | < 0.001* |
Killip class (%) | 0.325 | |||
I | 76.7 | 75.8 | 68.0 | |
II | 11.6 | 17.7 | 24.7 | |
III | 11.6 | 6.5 | 7.2 | |
Infarct-related vessel | a | b | a | 0.049* |
LAD (%) | 51.2 | 43.5 | 64.9 | |
LCX (%) | 7.0 | 8.1 | 8.2 | |
RCA (%) | 41.9 | 48.4 | 26.8 | |
Procedure | 0.586 | |||
POBA (%) | 4.7 | 0.8 | 2.1 | |
BMS (%) | 86.0 | 90.3 | 90.7 | |
DES (%) | 9.3 | 8.9 | 7.2 | |
Laboratory examination | ||||
Blood fasting sugar (mg/dL) | 124.05 ± 51.99 | 130.5 ± 48.93 | 141.9 ± 59.88 | 0.206 |
HbA1C (%) | 7.68 ± 2.19 | 7.19 ± 2.08 | 7.06 ± 2.08 | 0.382 |
Serum creatinine (mg/dL) | 1.35 ± 1.11 | 1.26 ± 1.06 | 1.52 ± 1.92 | 0.410 |
Total cholesterol (mg/dL) | 186.12 ± 43.03 | 190.01 ± 42.35 | 192.73 ± 44.47 | 0.703 |
LDL (mg/dL) | 119.33 ± 37.92 | 119.63 ± 37.19 | 122.71 ± 38.73 | 0.812 |
HDL (mg/dL) | 38.53 ± 7.95 | 41.16 ± 10.27 | 40.37 ± 10.61 | 0.340 |
Cardiac biomarker | ||||
Troponin-I (ng/mL) | ||||
initial | 4.01 ± 2.58a,b | 2.20 ± 5.30a | 5.07 ± 7.95b | 0.008* |
peak | 23.94 ± 26.59 | 19.20 ± 6.90 | 20.25 ± 11.88 | 0.415 |
CK-MB (ng/mL) | ||||
initial | 14.14 ± 19.89 | 15.79 ± 33.82 | 24.49 ± 42.68 | 0.152 |
peak | 74.36 ± 85.86 | 80.25 ± 133.29 | 60.93 ± 60.58 | 0.410 |
Peak CPK | 2081 ± 2258 | 2598 ± 2033 | 2314 ± 2505 | 0.416 |
Timing of primary PCI | ||||
Chest pain to reperfusion (minutes) | 298.7 ± 163.3 | 289.6 ± 164.5 | 296.4 ± 224.4 | 0.701 |
* Group 1: nitroprusside; Group 2: thrombectomy; Group 3: control.
* Data expressed as mean ± SD or % (n) of patients.
* Different letters (a, b, c) associated with different groups indicate significant difference (at 0.05 level) by Bonferroni multiple comparison procedure.
BMI, body mass index; BMS, bare metal stent; CK-MB, creatine kinase-MB; CPK, creatine phosphokinase; DES, drug-eluting stent; ESRD, end-stage renal disease; GRP, group; HDL, high-density lipoprotein; HF, heart failure; LAD, left anterior descending artery; LCX, left circumflex artery; LDL, low-density lipoprotein; RCA, right coronary artery; MI, myocardial infarction; PCI, percutaneous coronary interventions; POBA, pure balloon angioplasty; SBP, systolic blood pressure; SD, standard deviation.