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. 2015 Sep;31(5):398–405. doi: 10.6515/ACS20150424A

Table 4. Univariate and multivariate logistic regression models for variables of current smoker and former smoker associated with coronary artery plaque .

Never smoker (n = 864) Former smoker (n = 205) Current smoker with lower pack-year (n = 454, ≤ 20 pack-years) Current smoker with higher pack-year (n = 397, > 20 pack-years)
OR (95%CI) OR (95%CI) OR (95%CI) OR (95%CI)
Any plaque
Univariate 1 (ref) 0.885 (0.124-6.325) 0.238 (0.043-1.314) 1.382 (1.053-1.576)*
Multivariate 1 (ref) 1.258 (0.791-2.000) 0.918 (0.573-1.469) 1.598 (1.399-1.897)*
≥ 2/LM vessels disease
Univariate 1 (ref) 0.883 (0.655-1.190) 1.141 (0.743-1.752) 0.937 (0.661-1.328)
Multivariate 1 (ref) 0.589 (0.347-1.000) 0.769 (0.377-1.569) 0.702 (0.386-1.276)
Significant stenosis
Univariate 1 (ref) 1.402 (0.537-1.704) 1.703 (1.498-1.993)* 1.509 (1.398-1.650)*
Multivariate 1 (ref) 0.711 (0.448-1.127) 1.058 (1.042-1.075)* 1.830 (1.345-2.491)*
CACS ≥ 10
Univariate 1 (ref) 0.828 (0.623-1.100) 1.018 (0.682-1.521) 1.531 (1.025-1.738)*
Multivariate 1 (ref) 0.984 (0.938-1.031) 0.592 (0.312-1.124) 1.071 (1.051-1.093)*
Calcified plaque
Univariate 1 (ref) 1.651 (1.512-1.828)* 1.050 (0.749-1.471) 1.565 (1.428-1.746)*
Multivariate 1 (ref) 0.811 (0.464-1.416) 0.817 (0.512-1.303) 1.009 (0.967-1.052)
Non-calcified plaque
Univariate 1 (ref) 0.827 (0.590-1.160) 1.601 (1.473-1.763)* 1.629 (1.502-1.864)*
Multivariate 1 (ref) 0.831 (0.481-1.434) 1.034 (1.019-1.049)* 1.363 (1.018-1.826)*
Mixed plaque
Univariate 1 (ref) 0.904 (0.645-1.268) 0.677 (0.531-1.117) 1.548 (1.416-1.723)*
Multivariate 1 (ref) 0.695 (0.397-1.215) 0.636 (0.400-1.012) 1.063 (1.046-1.084)*

* Indicates vs. never smoker p < 0.05. The adjusted variables included age, BMI, family history of CAD, hypertension, diabetes mellitus, hyperlipidemia, stroke, TC, TG, LDL-C, HDL-C. Abbreviations are in Table 1 ,OR, odds ratio.