Table 4. Univariate and multivariate logistic regression models for variables of current smoker and former smoker associated with coronary artery plaque .
Never smoker (n = 864) | Former smoker (n = 205) | Current smoker with lower pack-year (n = 454, ≤ 20 pack-years) | Current smoker with higher pack-year (n = 397, > 20 pack-years) | |
OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | |
Any plaque | ||||
Univariate | 1 (ref) | 0.885 (0.124-6.325) | 0.238 (0.043-1.314) | 1.382 (1.053-1.576)* |
Multivariate | 1 (ref) | 1.258 (0.791-2.000) | 0.918 (0.573-1.469) | 1.598 (1.399-1.897)* |
≥ 2/LM vessels disease | ||||
Univariate | 1 (ref) | 0.883 (0.655-1.190) | 1.141 (0.743-1.752) | 0.937 (0.661-1.328) |
Multivariate | 1 (ref) | 0.589 (0.347-1.000) | 0.769 (0.377-1.569) | 0.702 (0.386-1.276) |
Significant stenosis | ||||
Univariate | 1 (ref) | 1.402 (0.537-1.704) | 1.703 (1.498-1.993)* | 1.509 (1.398-1.650)* |
Multivariate | 1 (ref) | 0.711 (0.448-1.127) | 1.058 (1.042-1.075)* | 1.830 (1.345-2.491)* |
CACS ≥ 10 | ||||
Univariate | 1 (ref) | 0.828 (0.623-1.100) | 1.018 (0.682-1.521) | 1.531 (1.025-1.738)* |
Multivariate | 1 (ref) | 0.984 (0.938-1.031) | 0.592 (0.312-1.124) | 1.071 (1.051-1.093)* |
Calcified plaque | ||||
Univariate | 1 (ref) | 1.651 (1.512-1.828)* | 1.050 (0.749-1.471) | 1.565 (1.428-1.746)* |
Multivariate | 1 (ref) | 0.811 (0.464-1.416) | 0.817 (0.512-1.303) | 1.009 (0.967-1.052) |
Non-calcified plaque | ||||
Univariate | 1 (ref) | 0.827 (0.590-1.160) | 1.601 (1.473-1.763)* | 1.629 (1.502-1.864)* |
Multivariate | 1 (ref) | 0.831 (0.481-1.434) | 1.034 (1.019-1.049)* | 1.363 (1.018-1.826)* |
Mixed plaque | ||||
Univariate | 1 (ref) | 0.904 (0.645-1.268) | 0.677 (0.531-1.117) | 1.548 (1.416-1.723)* |
Multivariate | 1 (ref) | 0.695 (0.397-1.215) | 0.636 (0.400-1.012) | 1.063 (1.046-1.084)* |
* Indicates vs. never smoker p < 0.05. The adjusted variables included age, BMI, family history of CAD, hypertension, diabetes mellitus, hyperlipidemia, stroke, TC, TG, LDL-C, HDL-C. Abbreviations are in Table 1 ,OR, odds ratio.