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Electromechanical effects of sitagliptin on pulmonary vein (PV). An example and average data (n = 7) show that the resting membrane potential (RMP), action potential amplitude (APA), action potential duration (APD) of PVs are not different between WKY and SHR with or without sitagliptin treatment. The SHR V had smaller contractile force than WKY PV. Treatment of sitagliptin significantly reduced the contractile forces of WKY PV, but did not change the contractile forces of SHR PV.
