Table 3. Multiple linear regression analysis of the relationship between CRP, components of metabolic syndrome, IL-6 and adipokines.
Model 1 | Model 2 | Model 3 | |||||||
Nonobese | Variables | β (se) | p | Variables | β (se) | p | Variables | β (se) | |
Systolic BP | 0.001 (0.002) | 0.784 | Systolic BP | 0.001 (0.002) | 0.656 | Systolic BP | < 0.001 (0.002) | 0.865 | |
Diastolic BP | 0.001 (0.004) | 0.713 | Diastolic BP | 0.001 (0.004) | 0.791 | Diastolic BP | 0.001 (0.004) | 0.692 | |
Triglyceride | 0.263 (0.121) | 0.031 | Triglyceride | 0.269 (0.120) | 0.026 | Triglyceride | 0.225 (0.122) | 0.065 | |
HDL-cholesterol | -0.002 (0.002) | 0.218 | HDL-cholesterol | -0.001 (0.002) | 0.635 | HDL-cholesterol | -0.001 (0.002) | 0.607 | |
IL-6 | 0.263 (0.059) | < 0.001 | IL-6 | 0.265 (0.059) | < 0.001 | IL-6 | 0.261 (0.059) | < 0.001 | |
Leptin | 0.190 (0.089) | 0.035 | Adiponectin | -0.256 (0.104) | 0.014 | LAR | 0.198 (0.064) | 0.002 | |
Obese | Model 1 | Model 2 | Model 3 | ||||||
Variables | β (se) | p | Variables | β (se) | p | Variables | β (se) | p | |
Systolic BP | 0.003 (0.003) | 0.267 | Systolic BP | 0.003 (0.003) | 0.245 | Systolic BP | 0.003 (0.003) | 0.276 | |
Diastolic BP | < 0.001 (0.004) | 0.678 | Diastolic BP | 0.001 (0.004) | 0.716 | Diastolic BP | < 0.001 (0.004) | 0.973 | |
Triglyceride | 0.242 (0.136) | 0.077 | Triglyceride | 0.216 (0.138) | 0.12 | Triglyceride | 0.198 (0.135) | 0.144 | |
HDL-cholesterol | -0.002 (0.003) | 0.443 | HDL-cholesterol | -0.001 (0.003) | 0.659 | HDL-cholesterol | -0.001 (0.003) | 0.815 | |
IL-6 | 0.299 (0.072) | < 0.001 | IL-6 | 0.343 (0.071) | < 0.001 | IL-6 | 0.310 (0.070) | < 0.001 | |
Leptin | 0.325 (0.119) | 0.007 | Adiponectin | -0.259 (0.124) | 0.038 | LAR | 0.310 (0.087) | < 0.001 |
* Adjusted for age, gender and smoking status.
Model 1: systolic BP, diastolic BP, triglyceride, HDL-cholesterol, IL-6 and leptin as the independent variables; Model 2: systolic BP, diastolic BP, triglyceride, HDL-cholesterol, IL-6 and adiponectin as the independent variables; Model 3: systolic BP, diastolic BP, triglyceride, HDL-cholesterol, IL-6 and LAR as the independent variables.
Abbreviations are presented as in Table 1.
Data with skew distribution (CRP, triglyceride, IL-6, leptin, adiponectin and LAR) are logarithmically transformed before statistical testing to meet the assumption of normal distributions.
The dependent variable is log CRP.
BP, blood pressure; HDL, high-density lipoprotein; IL-6, interleukin-6; LAR, leptin-to-adiponectin ratio.