Table 1. Clinical and demographic characteristics of the study patients .
Variable | All patients | Minimal-mild depression | Moderate-severe depression | Odds ratios (95% CI) | p value |
Age, (years) | 57.9 ± 14.4 | 55.5 ± 14.2 | 63.2 ± 13.2 | - | < 0.001 |
Male gender, n (%) | 201 (45) | 124 (46) | 69 (49) | 1.1 (0.7-1.7) | 0.6 |
Dyslipidemia, n (%) | 112 (25) | 69 (26) | 40 (28) | 1.1 (0.7-1.8) | 0.57 |
Diabetes mellitus n (%) | 140 (31) | 71 (26) | 64 (45) | 2.3 (1.5-3.5) | < 0.001 |
Hypertension n (%) | 248 (55) | 134 (50) | 109 (77) | 3.4 (2.1-5.4) | < 0.001 |
Smoking n (%) | 182 (41) | 117 (44) | 57 (40) | 0.9 (0.6-1.3) | 0.5 |
Family history of CAD, n (%) | 87 (19) | 66 (25) | 20 (14) | 0.5 (0.3-0.9) | 0.01 |
Previous MI n (%) | 91 (20) | 45 (17) | 46 (33) | 2.4 (1.5-3.9) | < 0.001 |
Previous CABG, n (%) | 58 (13) | 25 (9) | 33 (23) | 3.0 (1.7-5.2) | < 0.001 |
CAD, n (%) | 249 (56) | 140 (52) | 106 (75) | 2.8 (1.8-4.3) | < 0.001 |
Ischemic HF, n (%) | 233 (52) | 62 (23) | 125 (88) | 26 (14-47) | < 0.001 |
HF duration(years) | 6.6 ± 5.3 | 6.3 ± 4.9 | 7.2 ± 5.8 | - | 0.11 |
Hospitalization* | 1.8 ± 2.3 | 1.3 ± 2.0 | 2.5 ± 2.5 | - | < 0.001 |
NYHA class | - | < 0.001 | |||
Class 1, n (%) | 228 (51) | 213 (79)# | 5 (3.5)# | ||
Class 2, n (%) | 101(23) | 41 (15)# | 59 (42)# | ||
Class 3, n (%) | 31 (7) | 11 (4)# | 20 (14)# | ||
Class 4, n (%) | 60 (19) | 3 (1)# | 57 (40)# | ||
LVEF (%) | 54.2 ± 12.4 | 57.5 ± 9.6 | 47.5 ± 14.6 | - | < 0.001 |
BDI score | 12.4 ± 11.1 | 5.5 ± 4.7 | 25.5 ± 7.3 | - | < 0.001 |
BAI score | 13.4 ± 9.0 | 12.1 ± 8.1 | 15.8 ± 10.1 | - | < 0.001 |
BAI, Beck Anxiety Inventory; BDI, Beck Depression Inventory; CABG, coronary artery bypass grafting; CAD, coronary artery disease; HF, heart failure; LVEF, left ventricular ejection fraction; MI, myocardial infarction; NYHA, New York Heart Association.
* Number of hospitalizations in the last year. # Denotes significant column proportions by Chi-Square test.