Table 4. Changes of night-day ratio of 24-hour ambulatory pressure after add-on treatment with α1-blockers .
| Valsartan + Bunazosin (N = 47) | Valsartan + Doxazosin (N = 46) | p value (between groups) | |
| Night-Day SBP ratio | |||
| Start of add-on therapy | 0.93 ± 0.06 | 0.91 ± 0.07 | 0.208 |
| Study end | 0.91 ± 0.08 | 0.93 ± 0.09 | 0.262 |
| Change | -0.02 ± 0.08 | 0.02 ± 0.08 | 0.040 |
| p value (within group) | 0.115 | 0.375 | |
| Night-Day DBP ratio | |||
| Start of add-on therapy | 0.93 ± 0.08 | 0.91 ± 0.08 | 0.260 |
| Study end | 0.93 ± 0.09 | 0.95 ± 0.11 | 0.242 |
| Change | 0.00 ± 0.09 | 0.04 ± 0.09 | 0.038 |
| p value (within group) | 0.859 | 0.020 | |
| Night-Day mean BP ratio | |||
| Start of add-on therapy | 0.93 ± 0.07 | 0.91 ± 0.08 | 0.215 |
| Study end | 0.92 ± 0.08 | 0.94 ± 0.19 | 0.237 |
| Change | -0.01 ± 0.08 | 0.03 ± 0.08 | 0.032 |
| p value (within group) | 0.494 | 0.070 |
DBP, diastolic blood pressure; SBP, systolic blood pressure.