Table 2. Demographic characteristics of low LDL-C CAD patients in quartered HDL-C groups (N=165) .
| HDL category (mg/dl) | p value | ||||
| Very low (< 30) N = 24 | Low (30-39) N = 35 | Normal (40-59) N = 81 | High (≥ 60) N = 25 | ||
| Age, years (mean ± SD) | 70 ± 9 | 72 ± 8 | 71 ± 9 | 75 ± 7 | 0.164 |
| Male, N(%) | 16 (66.7) | 32 (91.4) | 68 (83.9) | 18 (72) | 0.060 |
| Hypertension, N(%) | 12 (50) | 21 (60) | 47 (58.0) | 15 (60) | 0.905 |
| Diabetes mellitus, N(%) | 12 (50)* | 8 (22.9) | 23 (28.4) | 7 (28) | 0.030 |
| Smoking, N(%) | 3 (12.5) | 8 (22.9) | 31 (38.3) | 9 (36) | 0.102 |
| CHF, N(%) | 5 (20.8) | 6 (17.1) | 16 (19.8) | 2 (8) | 0.505 |
| Body height, cm | 161 ± 8 | 162 ± 8 | 164 ± 7 | 161 ± 10 | 0.279 |
| Body weight, kg | 65.2 ± 14.7 | 62.4 ± 8.6 | 65.8 ± 11.2 | 61.8 ± 13.4 | 0.434 |
| Body mass index, kg/m2 | 24.8 ± 4.3 | 24.0 ± 3.2 | 24.4 ± 3.7 | 23.6 ± 3.7 | 0.696 |
| BP, systolic, mmHg | 122 ± 11 | 123 ± 13 | 123 ± 10 | 126 ± 10 | 0.668 |
| BP, diastolic, mmHg | 67 ± 12 | 69 ± 8 | 70 ± 10 | 68 ± 12 | 0.613 |
| Total cholesterol, mg/dl | 122 ± 25* | 139 ± 21# | 144 ± 22‡ | 157 ± 24 | < 0.001 |
| LDL-cholesterol, mg/dl | 72 ± 24 | 80 ± 15 | 72 ± 17 | 66 ± 21 | 0.054 |
| Triglyceride, mg/dl | 137 ± 59 | 121 ± 80 | 112 ± 71 | 103 ± 58 | 0.326 |
| Serum creatinine, mg/dl | 1.3 ± 0.5 | 1.3 ± 0.7 | 1.2 ± 0.5 | 1.2 ± 0.6 | 0.850 |
| C-reactive protein, mg/dl | 1.6 ± 2.1 | 1.0 ± 1.6 | 1.3 ± 1.9 | 2.1 ± 2.3 | 0.139 |
| Modified Gensini score | 18.9 ± 22.5 | 21.9 ± 29.5 | 23.8 ± 33.9 | 23.9 ± 30.8 | 0.942 |
| Number of CAD | 0.123 | ||||
| One-vessel disease | 16 (66.7) | 23 (65.7) | 47 (58) | 16 (64) | |
| Two-vessel disease | 5 (20.8) | 2 (5.7) | 22 (27.2) | 5 (20) | |
| Three-vessel disease | 3 (12.5) | 10 (28.6) | 12 (14.8) | 4 (16) | |
| LVEF, % | 34 ± 11† | 32 ± 11# | 36 ± 11 | 42 ± 8 | 0.046 |
BP, blood pressure; CHF, congestive heart failure; CKD, chronic kidney disease; LDL, low-density lipoprotein; LVEF, left ventricular ejection fraction.
* p < 0.05, very low HDL-C group compared to low, normal and high HDL-C group. # p < 0.05, low HDL-C group compared to high HDL-C group. † p < 0.05, very low HDL-C group compared high HDL-C group. ‡ p < 0.05, normal HDL-C group compared high HDL-C group.