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mRNA expression levels of SENP-1, HIF-1α and VEGF in pulmonary artery smooth muscle cells under normoxic and hypoxic conditions. Increasing expression levels of SENP-1, HIF-1α and VEGF were detected in the hypoxic group as exposure time was prolonged. Data are presented as the mean ± standard deviation. *P<0.05. SENP-1, small ubiquitin-like modifier-specific protease 1; HIF-1α, hypoxia-inducible factor-1α; VEGF, vascular endothelial growth factor.
