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Induction of Ara-C resistance in U937 cells cultured without serum. Following culturing of Ara-C sensitive U937 cells without serum, the U937 cells gained Ara-C resistance. The percentage of cell death by Ara-C treatment alone was significantly decreased with serum starvation. Ara-C, cytarabine arabinoside; AR, Ara-C-resistant; FITC, fluorescein isothiocyanate.
