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. 2016 Mar 4;13(4):3415–3422. doi: 10.3892/mmr.2016.4977

Figure 3.

Figure 3

YM155 induces the apoptosis of hypoxic human pulmonary artery smooth muscle cells. Apoptosis was determined using a TUNEL assay (scale bar=100 µm). Data are presented as the mean ± standard deviation (n=3). *P<0.05 vs. N group; **P<0.05 vs. H group. TUNEL, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling; YM155, sepantronium bromide; N, normoxia; H, hypoxia; NY, normoxia + 100 nmol/l YM155; HY1, hypoxia + 1 nmol/l YM155; HY10, hypoxia + 10 nM YM155; HY100, hypoxia + 100 nmol/l YM155.