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. 2016 Feb 15;13(4):2981–2990. doi: 10.3892/mmr.2016.4891

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Copyright: © Choi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of treadmill exercise on the cell proliferation in the SGZ. (A) Representative photomicrograph of BrdU immunostaining showing proliferating cells in the SGZ area 7 weeks after SC or 2VO surgery. Scale bars, 100 µm. (B) BrdU-stained cells were counted in the brain. Results are presented as the mean ± standard error of the mean, n=8. ^***P<0.001 vs. SC; ^#P<0.05 vs. 2VO. SC, sham-surgery group; SC+EX, sham-surgery group subjected to treadmill exercise (15 m/min, 30 min/day for 4 weeks); 2VO, 2VO surgery group; 2VO+EX, 2VO-surgery group subjected to treadmill exercise (15 m/min, 30 min/day for 4 weeks); SGZ, subgranular zone; BrdU, 5-bromo-2-deoxyuridine.