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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Eur Neuropsychopharmacol. 2016 Feb 10;26(4):653–662. doi: 10.1016/j.euroneuro.2016.02.009

Figure 3.

Figure 3

Mediation analyses. First, we established an effect of positive urine status (i.e., CUD+ versus controls) on metacognitive accuracy (c-paths). Second, we found an effect of positive urine status on the bilateral rACC GMV (a-paths). Third, controlling for positive urine status (where effects of CUD+ fell below significance: c′-paths), the (A) left rACC and (B) right rACC ROIs remained significant predictors of metacognitive accuracy (b-paths). Both indirect effects were significant, tested with bootstrapping, indicating mediation (see Results for statistics).