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. 2016 Mar 23;11(3):e0152317. doi: 10.1371/journal.pone.0152317

Table 1. NSCLC patient characteristics according to COPD status.

Characteristics COPD (%) N = 193 Non-COPD (%) N = 132 p-value
Sex
 Female 77 (51) 74 (49) 0.004
 Male 116 (66.7) 58 (33.3)
Age at diagnosis, Mean (±SD) 65.6 (±9.9) 60.6 (±10.8) <0.001*
Histology
 Adenocarcinoma 154 (59) 107 (41) 0.777
 Adeno-squamous 14 (66.7) 7 (33.3)
 NSCLC-NOS 25 (58.1) 18 (41.9)
Smoking status#
 Current or past smoker 184 (62.6) 110 (37.4) <0.001
 Non-smoker 4 (18.2) 18 (81.8)
FEV1%, Mean (±SD) 72.8 (±18.7) 90.2 (±19.4) -
FEV1/FVC ratio, Mean (±SD) 0.58 (±0.09) 0.76 (±0.05) -
KRAS mutation#
 Yes 66 (62.9) 39 (37.1) 0.404
 No 127 (58) 92 (42)
EGFR activating mutation#
 Yes 9 (31) 20 (69) 0.001
 No 180 (61.9%) 111 (38.1)

* T-test;

Chi-square test;

#Missing data for smoking (n = 9), KRAS (n = 1) and EGFR (n = 5) status.