Table 1. NSCLC patient characteristics according to COPD status.
Characteristics | COPD (%) N = 193 | Non-COPD (%) N = 132 | p-value |
---|---|---|---|
Sex | |||
Female | 77 (51) | 74 (49) | 0.004† |
Male | 116 (66.7) | 58 (33.3) | |
Age at diagnosis, Mean (±SD) | 65.6 (±9.9) | 60.6 (±10.8) | <0.001* |
Histology | |||
Adenocarcinoma | 154 (59) | 107 (41) | 0.777† |
Adeno-squamous | 14 (66.7) | 7 (33.3) | |
NSCLC-NOS | 25 (58.1) | 18 (41.9) | |
Smoking status# | |||
Current or past smoker | 184 (62.6) | 110 (37.4) | <0.001† |
Non-smoker | 4 (18.2) | 18 (81.8) | |
FEV1%, Mean (±SD) | 72.8 (±18.7) | 90.2 (±19.4) | - |
FEV1/FVC ratio, Mean (±SD) | 0.58 (±0.09) | 0.76 (±0.05) | - |
KRAS mutation# | |||
Yes | 66 (62.9) | 39 (37.1) | 0.404† |
No | 127 (58) | 92 (42) | |
EGFR activating mutation# | |||
Yes | 9 (31) | 20 (69) | 0.001† |
No | 180 (61.9%) | 111 (38.1) |
* T-test;
†Chi-square test;
#Missing data for smoking (n = 9), KRAS (n = 1) and EGFR (n = 5) status.