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. Author manuscript; available in PMC: 2016 Mar 23.
Published in final edited form as: Leuk Res. 2011 Feb 12;35(6):814–820. doi: 10.1016/j.leukres.2010.12.028

Figure 2. Effects of 3-BrOP on proliferation, survival and cell death.

Figure 2

A, Proliferation and survival was measured via serial cell counts following treatment with 3-BrOP at 10 mcM for Nalm6 (pre-B ALL) and 20 mcM for Molt4 (T-ALL). Average +/− SD of three samples shown. B, Induction of cell death was assessed in Nalm6 (pre-B ALL) and U937 (AML) cells treated with 30mcM 3-BrOP for 24 or 48 hours by measuring the percentage of cells with less than 2N (sub-G0) DNA content by propidium iodide (PI) staining with flow cytometry. Average +/− SD of three samples shown. C, Cell death was also measured after 48 hours exposure to increasing concentrations of 3-BrOP. AnnexinV-APC conjugate was used and the percent of cells which are AnnexinV-positive is indicated.