Table 4. PEA15 population and permeability quantitation.

Given are mean and SEM of percent PEA15-positive (PEA15+, green) and PEA15-negative (PEA15−, white) CON and STAT3-CKO astrocytes for unstretched (n=5 mice of each genotype), acute post-injury (combining same trend 5 min and 30 min post-injury data, n=10 CON and 5 STAT3-CKO mice) and 48 h post-injury cultures (n=5 mice of each genotype). Percent membrane permeable cells were determined of all cells and for PEA15-positive and −negative fractions (PI-positive, PI+ pink columns).

		%	PEA15+		PEA15-
Genotype	Time post-injury	PI+		PI+ of PEA15+		PI+ of PEA15-
CON	unstr	N/A	98 ± 1	N/A	2 ± 1	N/A
	acute	22 ± 7	79 ± 5	5 ± 3	21 ± 5	78 ± 12
	48 h	16 ± 9	83 ± 6	3 ± 2	17 ± 6	73 ± 26
STAT3 CKO	unstr	N/A	95 ± 5	N/A	5 ± 5	N/A
	acute	44 ± 11	58 ± 9	6 ± 2	43 ± 9	91 ± 11
	48h	53 ± 6	52 ± 9	12 ± 3	48 ± 9	98 ± 1